p-Cymenesulphonyl Chloride: A Bio-Based Activating Group and Protecting Group for Greener Organic Synthesis
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چکیده
منابع مشابه
3,3(')-Oxybis(dimethoxytrityl chloride) (O-DMTCl): synthesis and applications of a novel bifunctional protecting group.
3,3(')- Oxybis(dimethoxytrityl chloride) (O-DMTCl) was synthesized as a novel, acid-labile bifunctional protecting reagent. The reactions of O-DMTCl with base-protected ribonucleosides afforded unexpectedly 2('),5(')-cyclic protected ribonucleosides in addition to the expected 3('),5(')-cyclic protected ribonucleosides in good yields.
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This review is intended to provide the reader who is interested in the historical development of the recent research on photoremovable protecting groups, phototriggers, and “caged” compounds and to provide some insight into the genesis of our entry into the field through our most recent discoveries. Several other investigations have paralleled our development of a photoremovable protecting grou...
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24 W. Lin, D.S. Lawrence, J. Org. Chem. 2002, 67, 2723–2726. 25 H.J. Montgomery, B. Perdicakis, D. Fishlock, G.A. Lajoie, E. Jervis, J.G. Guillemette, Bioorg. Med. Chem. 2002, 10, 1919–1927. 26 M. Lu, O.D. Fedoryak, B.R. Moister, T.M. Dore, Org. Lett. 2003, 5, 2119– 2122. 27 V.G. Robu, E.S. Pfeiffer, S.L. Robia, R.C. Balijepalli, Y. Pi, T. J. Kamp, J.W. Walker, J. Biol. Chem. 2003, 278, 48154–4...
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A number of 5'-O-(4,4'-dimethoxytrityl)thymidine N,N-diisopropylamino phosphoramidites protected at P(III) with derivatives of 2-benzamidoethanol were synthesized and incorporated into synthetic oligonucleotides. Depending on substitution patterns at the alkyl chain, amido group, and phenyl ring, the time required for removal of these protecting groups using concentrated ammonium hydroxide vari...
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ژورنال
عنوان ژورنال: Journal of the Brazilian Chemical Society
سال: 2015
ISSN: 0103-5053
DOI: 10.5935/0103-5053.20150169